Mgr. Vladimír Rotrekl, Ph.D.
Head of the research group, Vladimír Rotrekl Research Group
| phone: | +420 549 49 8002 |
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Cellular Biology
Vladimír Rotrekl RG: Embryonic and Pluripotent Stem Cell
Key Topics:
- Genomic stability and metabolism of human pluripotent stem cells
- Heart failure modeling using pluripotent stem cells
Stjepan Uldrijan RG: Cancer Biology
- Regulation of the p53 tumour suppressor by oncoproteins MDM2 and MDMX
- Targeted therapy for malignant melanoma
Mgr. Bc. Stjepan Uldrijan, CSc.
Head of the research group, Stjepan Uldrijan Research Group
| phone: | +420 549 49 4040 |
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| web: | https://biology.med.muni.cz/en/research/david-smajs-group/about |
Sabina Ševčíková RG: Monoclonal Gammopathies and their Molecular Origin
- Pathogenesis of monoclonal gammopathies, especially multiple myeloma and plasma leukemia
- Plasma cell leukaemia
- Liquid biopsies (biopsies of body fluids)
doc. RNDr. Sabina Ševčíková, Ph.D.
Head of the research group, Sabina Ševčíková Research Group: Monoclonal Gamapathies and their Molecular Origin
| phone: | +420 549 49 3380 |
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| web: | https://biology.med.muni.cz/en/research/david-smajs-group/about |
Department of Histology and Embryology
Key Topics:
- Biology of stem and progenitor cells, application in biomedicine
- Aspects of pluripotent stem cells with a main focus on genomic stability
- Modeling neural differentiation in vitro using human pluripotent stem cells
- Human pluripotent stem cells derived retinal organoids with a special focus on non-coding microRNA and rare disease modeling
- Translational aspects of stem cells and their derivatives, including the safety issues related to SC stability and developing recommendations for GMP production and quality control of ATMP
- Development of 3D cell culture platforms, tools to study SC differentiation and communication, methods for bioprinting of SC in hydrogels, and microfluidic systems for long-term 3D culture and studying ex vivo morphogenesis
doc. MVDr. Aleš Hampl, CSc.
Department head, Department of Histology and Embryology
| phone: | +420 549 49 3514 |
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