Stem Cell Research

Department of Histology and Embryology

Key Topics:

  • Biology of stem and progenitor cells, application in biomedicine
  • Aspects of pluripotent stem cells with a main focus on genomic stability
  • Modeling neural differentiation in vitro using human pluripotent stem cells
  • Human pluripotent stem cells derived retinal organoids with a special focus on non-coding microRNA and rare disease modeling
  • Translational aspects of stem cells and their derivatives, including the safety issues related to SC stability and developing recommendations for GMP production and quality control of ATMP
  • Development of 3D cell culture platforms, tools to study SC differentiation and communication, methods for bioprinting of SC in hydrogels, and microfluidic systems for long-term 3D culture and studying ex vivo morphogenesis

doc. MVDr. Aleš Hampl, CSc.

Department head, Department of Histology and Embryology

Phone: +420 549 49 3514

Vladimír Rotrekl RG: Genomic stability of pluripotent stem cells

Key Topics:

  • Embryonic and Induced Pluripotent Stem Cell
  • Heart failure modeling using pluripotent stem cells

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