National Institute of Virology and Bacteriology (NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- doc. Mgr. Pavel Plevka, Ph.D.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel J. Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
- Faculty of Science
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 28
2023
-
Escherichia coli from biopsies differ in virulence genes between patients with colorectal neoplasia and healthy controls
Frontiers in Microbiology, year: 2023, DOI
-
Novel antimicrobial genetic elements in methicillin-resistant Macrococcus armenti
Microbial Drug Resistance, year: 2023, volume: 29, edition: 2, DOI
-
Staphylococcus aureus Prophage-Encoded Protein Causes Abortive Infection and Provides Population Immunity against Kayviruses
mBio, year: 2023, volume: 14, edition: 2, DOI
-
Staphylococcus brunensis sp. nov. isolated from human clinical specimens with an SCC-related genomic island outside of the rlmH gene bearing ccrDE recombinase gene complex (LB068)
Year: 2023, type: Conference abstract
-
Translation machinery captured in motion
Wiley Interdisciplinary Reviews: RNA, year: 2023, DOI
2022
-
Alternative antibacterial therapy using bacteriophages: Phage host interactions and phage therapy safety
Year: 2022, type: Conference abstract
-
BIOCHEMICAL ANALYSIS OF COMPLEX FORMATION BETWEEN RNA POLYMERASE AND RIBOSOME
Year: 2022, type: Conference abstract
-
Capillary electrophoretic methods for classification of methicillin-resistant Staphylococcus aureus (MRSA) clones
Analytica Chimica Acta, year: 2022, volume: 1227, edition: September, DOI
-
CELLULAR COLOCALIZATION OF TRANSCRIPTION AND TRANSLATION
Year: 2022, type: Conference abstract
-
Cryo-electron microscopy and image classification reveal the existence and structure of the coxsackievirus A6 virion
Communications Biology, year: 2022, volume: 5, edition: 1, DOI