Success Stories

The second spin-off of Faculty of Medicine EQUILIO - Czech Institute of Dialectic Behavioral Therapy

The second spin-off of Faculty of Medicine EQUILIO - Czech Institute of Dialectic Behavioral Therapy

The second spin-off company of the Faculty of Medicine at Masaryk University, named EQUILIO – Czech Institute of Dialectical Behavior Therapy, has been established. The company was founded by Dr. Pavla Horká Linhartová and psychotherapist Martin Horký from the Department of Psychiatry at Brno University Hospital and the Faculty of Medicine, Masaryk University, with the aim of educating professionals and expanding the use of this still underutilized method in the Czech Republic. Dialectical Behavior Therapy (DBT) combines elements of dialectics, cognitive behavioral therapy, and Zen Buddhism, and focuses on balance, mindfulness, acceptance, change, and working with maladaptive patterns of thinking. The press release announcing the establishment of the company is available here.

The first spin-off company of Faculty of Medicine

The first spin-off company of Faculty of Medicine

In April, the first spin-off company of the Faculty of Medicine of Masaryk University called MilkyWay be well was established. The company as such was founded in 2021 by the husband and wife team of Martin and Barbora Bořil. Martin's last work experience brought him to doc. PhDr. Miroslav Světlák, PhD., the head of the Institute of Medical Psychology and Psychosomatics at the MED MUNI. Their shared enthusiasm for improving mental health led to the creation of an innovative mobile app designed for cancer patients and their mental health. Thanks to their collaboration, the aforementioned spin-off company was created, which aims to improve mental health through eHealth tools implemented in the work environment to prevent mental illness.

Analysis of types of cell death for experimental drug development

Analysis of types of cell death for experimental drug development

The aim of the Proof of Concept project, whose main researcher is RNDr. Jan Balvan, Ph.D. from the Department of Pathophysiology of the Faculty of Medicine of Masaryk University and which was supported this year within the TA CR GAMA 2 programme, is the development of a robust method enabling automatic detection and resolution of cell death subtypes based on their phase dynamics captured by holographic microscopy. This method has a high potential for cytotoxicity and biocompatibility testing in the development of new drugs and materials. You can find the interview with Dr. Balvan here.

Analysis of epidemiological situations

Analysis of epidemiological situations

In 2020, the Proof of Concept project of prof. RNDr. Ladislav Dušek, Ph.D. from the Institute of Biostatistics and Analyses called Online platform for real-time monitoring, analysis and management of epidemic situations. The output is a web application Monitoring, analysis and management of epidemic situations (MAMES, https://mames.iba.muni.cz). It enables the general public to model the development of the COVID-19 epidemic in real time and thus responds to the current need for the rapid availability of adequate information related to the spread of the disease.

Development of oncological drugs

Development of oncological drugs

An intensive programme of development of oncological drugs based on the know-how co-developed by LF MU under a license agreement with Artios Pharma Ltd. is underway. The research is focused on inhibition of nucleases by patented compounds developed in the laboratories of the scientific teams of doc. Kamil Paruch and doc. Lumír Krejčí from the Faculty of Science and Faculty of Medicine of MU. Artios Pharma Ltd. announced a three-year research collaboration with Merck KGaA in 2020 to discover and develop several new cancer drugs.

Evaluation of the effect of stress

Evaluation of the effect of stress

Under the leadership of prof. MUDr. Julie Dobrovolná, Ph.D., a new MU spin-off company called Entrant s.r.o. was established, focused on the evaluation of the impact of stress on humans in various situations, especially in fields where stress plays a key role. The device that will be developed may help soldiers, pilots and astronauts in the future. The technology received the support of the space incubator ESA.BIC Brno.

In vitro system for preclinical embryotoxicity testing

In vitro system for preclinical embryotoxicity testing

Within the framework of the TA ČR project GAMA 2 Proof of Concept by PharmDr. Zuzana Holubcová, Ph.D. (from the Institute of Histology and Emryology, Faculty of Medicine, Masaryk University) called MUNI-BLAST, an in-vitro system based on 3D structures resembling human embryos at the blastocyst stage (so-called blastoids) will be developed and tested, which has the potential to eliminate false-negative results and the need to use a large number of laboratory animals.

New biotechnology for milk production

New biotechnology for milk production

The technology of milk production in mammary gland organoids will be verified and upscaled within the Proof of Concept project by Mgr. Zuzana Koledová, Ph.D. from the Institute of Histology and Emryology, Faculty of Medicine, Masaryk University. The MUNI-MILK project was supported by the TA ČR GAMA 2 programme. The technology targets the new, emerging market of food created by biotechnology.

All activities in this field were implemented with the support of the Technology Transfer Office.

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💡 Results in 2025:

  • utility model „A biofilm model for testing antimicrobial agents
  • brazilian patent „POLIPEPTÍDEO TERMOESTÁVEL E MEIO DE CULTURA (Thermostable FGF2 polypeptide, use thereof)
  • Trademark „FlyCellix
  • Trademark "FAIR MEDICINE by CREATIC"
  • Trademark "MyDendritte"
  • prototype/functional sample Functional multilayer cellular skin substitute
  • verified technology „Production of a multilayer cellular skin substitute based on biocompatible foam scaffolds and cultured autologous/allogeneic MSCs and keratinocytes

💡 Results in 2024:

  • utility model „An antimicrobial polysaccharide transparent film for the treatment of early infections
  • utility model „An injectable gel from natural resin with bacteriophages for the healing of infected wounds
  • utility model „A microfluidic chip and an analytic assembly for the characterization and identification of microbes using optical detection methods

  Contact

Ing. Karolína Kašparová

Office for Research and Quality

e‑mail:

Photo by CHUTTERSNAP on Unsplash, Photo by National Cancer Institute on Unsplash, Photo by Kristopher Allison on Unsplash, Photo by Clay Banks on Unsplash

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