Pyrazolotriazines as inhibitors of nucleases

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Authors

DAMBORSKÝ Jiří NIKULENKOV Fedor SISÁKOVÁ Alexandra HAVEL Štěpán KREJČÍ Lumír CARBAIN Benoit Jean-Pierre BREZOVSKÝ Jan DANIEL Lukáš PARUCH Kamil

Year of publication 2018
Type Patent
MU Faculty or unit

Faculty of Science

Publisher USPTO
State USA
Patent's number US 9969741 B2
Web http://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=/netahtml/PTO/search-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN/9969741
Description The present invention relates to substituted heterocycles as inhibitors of nudeases MUS81 and MRE11, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer.
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