Chirurgická léčba mozkových metastáz

Title in English Surgical treatment of brain metastases
Authors

VYBÍHAL Václav SMRČKA Martin ROŠKOVÁ Ivana KAZDA Tomáš ŠPRLÁKOVÁ-PUKOVÁ Andrea ŠÁNA Jiří SLABÝ Ondřej VEČEŘA Marek KŘEN Leoš FADRUS Pavel

Year of publication 2020
Type Article in Periodical
Magazine / Source Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2020-2-4/surgical-treatment-of-brain-metastases-121846?hl=cs
Doi http://dx.doi.org/10.14735/amcsnn2020157
Keywords brain metastasis; resection; surgical treatment
Description Brain metastases are serious complication of cancer. Progress in brain imaging, intraoperative electrophysiological monitoring and neurosurgical equipment have increased the extent of the resection and safety of neurosurgical operations while reducing mortality and morbidity. Surgical resection is still the first considered therapeutic option. It is especially recommended for patients with solitary cerebral metastasis in accessible localization, in good clinical conditions and with favourable prognosis. It is relatively contraindicated in the case of uncontrolled cancer disease, poor clinical conditions, in the case of radiosensitive tumours, poor disease prognosis and presence of more than three cerebral metastases. Surgical therapy for two or three metastases is also possible, but its role may be questionable in some aspects. General recommendations are not clearly defined in the case of recurrent metastases as well, and individual assessment is preferred based on the evaluation of the number of prognostic factors.

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