Akutní pankreatitida - validace nové klasifikace na souboru 159 nemocných a prognostické faktory

Title in English Acute pancreatitis - Validation of Revised Atlanta Classification on 159 patients and prognostic factors


Year of publication 2014
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Field Other specializations of internal medicine
Keywords acute pancreatitis; Atlanta classification; severe; moderately severe; mild; leucocyte count; RDW
Attached files
Description Introduction: In the last few years the Atlanta clasification of acute pancreatitis(AP) have been revised. However prognostic markers of AP are still being searched for. The aim of this study is to validate the 3 severity cathegories proposed by the revised Atlanta classification. We also tried to reevaluate the association between two laboratory markers (leucocyte count and RDW-red cell distribution width) on admission and prognosis of the patients with AP. Methods: 159 patients were included into the study. The patients were classified according to revised Atlanta criteria and the subgroups evaluated according to mortality, lenght of hospital stay and need for interventions. Leucocyte count and RDW on admission was evaluated in the patients. Results: All the subgroups of patients were associated with significantly relevant differences in mortality, lenght of hospital stay and need for operations on pancreas. Leucocyte count and RDW were identified as significant predictors for severe AP and RDW was also identified as significant predictor for mortality in patients with AP. Conclusion: New categories of severity as defined by Revised Atlanta classification are describing well the mortality, lenght of hospital stay and need for interventions in the patients with AP. Leucocyte count and RDW on admission are needed to be confirmed as potential prognostic markers of severity and mortality in AP.

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