Autoprotilátky u systémových onemocnění pojiva a ANCA asociovaných vaskulitid, jejich vztah k intersticiálním plicním procesům a prognóze
| Title in English | Autoantibodies in systemic connective tissue disease and ANCA-associated vasculitis, their relationship to interstitial diseases and prognosis |
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| Authors | |
| Year of publication | 2017 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Pneumology |
| Keywords | autoantibodies; connective tissue disease; interstitial lung diseases; prognosis; vasculitis |
| Description | Lung disease, including interstitial lung disease (ILD), is a frequent complication of systemic connective tissue disorders (CTD) and ANCA (anti-neutrophil cytoplasmic antibody) associated vasculitis (AAV). Pulmonary manifestations are prognostic factor of CTDs and vasculitis. Autoantibodies assessment is a part of differential diagnosis algorithm of lung diseases. Autoantibodies importance is mainly clinical-diagnostic. Using detection of some autoantibodies it is possible to determine prognosis of lung involvement, especially in CTDs. |