Hypolipidemika a cílové hodnoty lipidů

Title in English Hypolipidemic treatment and target values of lipids

KYSELÁK Ondřej SOŠKA Vladimír

Year of publication 2018
Type Article in Periodical
Magazine / Source Interní medicína pro praxi
MU Faculty or unit

Faculty of Medicine

Keywords dyslipidemia; cardiovascular diseases; LDL cholesterol; triglycerides; statins; PCSK9 inhibitors
Description Hypolipidemics are one of the most frequently prescribed drugs in the world. Last year, the updated guidelines were released:European Guidelines on cardiovascular disease prevention in clinical practice by European Society of Cardiology (ESC) and ESC/EAS (European Atherosclerosis Society) Guidelines for the Management of Dyslipidaemias. Both of them contain changes mainlyin estimation of individual cardiovascular risk and target levels of LDL-cholesterol. Targeting these goals is usually very difficultand often impossible in patients with familial hypercholesterolemia. PCSK9 inhibitors are a new and very potent hypolipidemicsthat should make target LDL-cholesterol levels reachable.

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