Fast and accurate compensation of signal offset for T2 mapping

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Authors	MICHÁLEK Jan HANZLÍKOVÁ Pavla TRINH Tuan PACÍK Dalibor
Year of publication	2019
Type	Article in Periodical
Magazine / Source	Magnetic Resonance Materials in Physics, Biology and Medicine
MU Faculty or unit	Faculty of Informatics
Citation
Web	https://doi.org/10.1007/s10334-019-00737-3
Doi	http://dx.doi.org/10.1007/s10334-019-00737-3
Keywords	Algorithms; Least-squares analysis; Software
Description	T2 maps are more vendor independent than other MRI protocols. Multi-echo spin-echo signal decays to a non-zero offset due to imperfect refocusing pulses and Rician noise, causing T2 overestimation by the vendor's 2-parameter algorithm. The accuracy of the T2 estimate is improved, if the non-zero offset is estimated as a third parameter. Three-parameter Levenberg--Marquardt (LM) T2 estimation takes several minutes to calculate, and it is sensitive to initial values. We aimed for a 3-parameter fitting algorithm that was comparably accurate, yet substantially faster.
Related projects:	National research infrastructure for biological and medical imaging