Cytochemická detekce zdrojů peroxidu vodíku v kultivačním systému v průběhu fertilizace in vitro u člověka
| Title in English | Cytochemical detection of the hydrogen peroxide sources in culture system during human in vitro fertilisation |
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| Authors | |
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Scripta Medica |
| MU Faculty or unit | |
| Citation | |
| Field | Gynaecology and obstetrics |
| Keywords | cytochemistry; hydrogen peroxide; in vitro fertilisation |
| Description | Cellular sources of hydrogen peroxide were detected cytochemically in culture system during IVF. The spermatozoa (especially frozen-thawed), damaged cumulus cells as well as fragmented oocytes and developmentally arrested embryos have been identified as hydrogen peroxide generators. Production of this metabolite is associated with cell damage and/or degeneration signalling the poor quality of gametes and accompanying somatic cells. |
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