Vliv farmakologické manipulace s 5-HT1A receptorovým podtypem na sociální chování myší

Title in English Influence of pharmacological manipulation with 5-HT1A receptor subtype on social behaviour in mice
Authors

NOVÁKOVÁ Jana VINKLEROVÁ Jana ŠULCOVÁ Alexandra

Year of publication 2002
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords 5-HT1A receptor subtype; social behaviour; mice
Description The present study investigated the influence of ligand of 5-HT1A receptor ligand S 15535 which acts as an agonist and an antagonist at presynaptic and postsynaptic sites respectively, on agonistic behaviour in mice. In conclusion, S 15535 exerted marked antiaggressive action in aggressive mice with less pronounced effect on defensive-ascape behaviour in timid animals.
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