Caffeic acid enhances differentiation of HL-60 myeloid leukemia cells induced by all-trans retinoic acid

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Authors

VESELSKÁ Renata ZITTERBART Karel AUER Jan NERADIL Jakub

Year of publication 2003
Type Article in Proceedings
Conference Progress in Basic, Applied and Diagnostic Histochemistry
MU Faculty or unit

Faculty of Medicine

Citation
Field Morphological specializations and cytology
Keywords caffeic acid; all-trans retinoic acid; induced differentiation; HL-60 cells
Description The course of differentiation of HL-60 cells was studied by detecting the occurrence of functionally mature granulocytes and CD-66b expressing cells in ATRA- and/or CA-treated cell populations. Application of CA alone had no or minimal influence on cell differentiation whereas differentiating activity of ATRA was potentiated by CA treatment.
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