A Method for Detecting Breakpoints in Array CGH data



Year of publication 2005
Type Article in Proceedings
Conference EnviroInfo Brno 2005. Networking Environmental Information. Part 2. Proceedings of the 19th International Conference Informatics for Environmental Protection.
MU Faculty or unit

Faculty of Medicine

Field Applied statistics, operation research
Keywords array CGH; breakpoint detection; analysis; microarray
Description In present, microarray CGH experiments became a powerful technique for analysing changes in DNA, by comparing control DNA and DNA of interest. This is widely used for example in genome cancer or species distin-guishing studies. The method produce huge amount of data and special statistic techniques for detecting copy number changes regions are necessary. We propose a new method for detecting breakpoints in DNA. The performance of the method is demonstrated using publicly available data set.
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