The influence of mild hypothermia on ICP, CPP and outcome in patients with primary and secondary brain injury


SMRČKA Martin VIDLÁK Milan MÁCA Karel SMRČKA Vladimír GÁL Roman

Year of publication 2005
Type Article in Periodical
Magazine / Source Acta Neurochirurgica
MU Faculty or unit

Faculty of Medicine

Field Neurology, neurosurgery, neurosciences
Keywords Severe head injury; primary and secondary brain damage; mild hypotermia
Description Aim of this study was to examine the hypothesis that only a subgroup of patinets with lesser primary brain damage after severe head injury may benefit from therapeutic hypothermia. Hypothermia decreased ICP and increased CPP regardless of the type of brain injury. Hypothermia was not able to improve outcome in patients with primary brain lesions but this pilot study suggests that it significantly improves outcome in patients with extracerebral hematomas.

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