Analyses of recombinant activated factor VII treatments from clinical practice for rapid bleeding and acute pain control in haemophilia patients with inhibitors

Authors

SALAJ Peter OVESNÁ Petra PENKA Miroslav HEDNER Ulla

Year of publication 2012
Type Article in Periodical
Magazine / Source Haemophilia
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1111/j.1365-2516.2012.02920.x
Field Oncology and hematology
Keywords bleeding disorders; inhibitor
Description Haemophilia registries, such as HemoRec, provide a valuable source of real-world data for the study of treatment modalities. We have reported that early treatment with rFVIIa appeared more effective than delayed-onset treatment in controlling the incidence of re-bleeding. The current study investigated whether time to treatment and/or initial dose of rFVIIa affects bleeding duration and, for the first time, their impact on acute pain control in inhibitor patients.

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