DIOS - database of formalized chemotherapeutic regimens


KLIMEŠ Daniel ŠMÍD Roman KUBÁSEK Miroslav VYZULA Rostislav DUŠEK Ladislav

Year of publication 2013
Type Article in Periodical
Magazine / Source Studies in Health Technology and Informatics
MU Faculty or unit

Faculty of Medicine

Field Informatics
Keywords cancer chemotherapy protocols; antineoplastic combined chemotherapy regimens; XML; clinical database
Attached files
Description Chemotherapeutic regimens (CHR) and their administration are routine practice in contemporary oncology. The development of a structured, electronic database of standard CHR can help the faster propagation of information about new CHR and at the same time enable assessment of their adherence in clinical practice. The goal was to develop a standardized way to describe a regimen using XML, fill the database with currently available regimens and develop tools to assess the adherence of the treatment to chosen regimen, compare the dose-intensity and recognize the regimen from existing data on drug administration. The data are being inserted in cooperation with expert oncologists and the database currently contains about 260 CHRs. Such system can be used to enhance decision support systems and interoperability of HIS. The database and tools are available online on the internet.
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