Co je nového v srdečním selhání se zachovalou ejekční frakcí levé komory za posledních pět let?
| Title in English | What is new in heart failure with preserved ejection fraction within last five years? |
|---|---|
| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.vnitrnilekarstvi.eu/vnitrni-lekarstvi-clanek/co-je-noveho-v-srdecnim-selhani-se-zachovalou-ejekcni-frakci-leve-komory-za-poslednich-pet-let-49406 |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | diastolic dysfunction; heart failure; left ventricle; preserved ejection fraction of left ventricle |
| Description | Heart failure with preserved ejection fraction of left ventricle (HFPEF) is frequent disease with serious consequences. Incidence of HFPEF in population still growing. The exact pathophysiological mechanism of HFPEF remain unclear. Recent evidence suggests a relationship between inflammation associated with obesity and diabetes mellitus and progression of HFPEF. Consistently it has been reported that serum concentration of some pro-inflamantory markers such as adiponectin is positively related to HFPEF. By HFPEF is attended diastolic dysfunction. Diastolic dyfunction is linked to many other cardiac and non-cardiac diseases. Despite the great effort and new therapeutic approaches the prognosis of HFPEF does not improve. |