Novinky v diagnostice a léčbě MEN1
| Title in English | News in diagnostics and therapy of multiple endocrine neoplasia type 1 |
|---|---|
| Authors | |
| Year of publication | 2015 |
| Type | Article in Periodical |
| Magazine / Source | Vnitřní lékařství |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | endosonography; chromogranin A; menin; multiple endocrine neoplasia type 1; neuroendocrine tumor; pituitary adenoma; primary hyperparathyroidism |
| Description | MEN1 syndrome is an autosomal dominant disorder caused by mutation in the menin gene located on the 11th chromosome. It involves functional or cancerous diseases of parathyroid glands, hypophysis, endocrine pancreas, adrenal glands, or other tumors. The diagnosis of MEN1 is su¬spected if at least 2 components of this multiple tumor syndrome occur simultaneously. The increase in diagnostic precision enables detection of MEN1 in its early stages. Currently, the most frequently discussed topics include the use of biomarkers for diagnostics and new approaches in surgical treatment of MEN1. |