Imunoterapie v prevenci a léčbě karcinomu prsu

Warning

This publication doesn't include Faculty of Medicine. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.

Title in English	Immunotherapy for the Prevention and Treatment of Breast Cancer
Authors	SVOBODA Marek NAVRÁTIL Jiří SLABÝ Ondřej
Year of publication	2015
Type	Article in Periodical
Magazine / Source	Klinická onkologie
MU Faculty or unit	Central European Institute of Technology
Citation
Field	Oncology and hematology
Keywords	immunotherapy; breast cancer; prevention; vaccine; immune checkpoints
Description	The immune system is believed to play a dual role in carcinogenesis. On one hand, it could prompt tumorigenesis and cancer progression, on the other hand, it has the capacity to eradicate tumor cells. There has been an evidence of natural immunogenicity in breast cancer and we have also witnessed several attempts to stimulate non-specific antitumor immune response (Coleys toxin, BCG vaccine etc.). New technologies and further knowledge of molecular basis of immune system and its function encouraged the development of effective immunotherapy capable of inducing a solid antitumor activity.