Superiority of SPECT/CT over planar I-123-mIBG images in neuroblastoma patients with impact on Curie and SIOPEN score values
| Authors | |
|---|---|
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Nuklearmedizin |
| MU Faculty or unit | |
| Citation | |
| Web | http://nuk.schattauer.de/inhalt/archivestandard/issue/2381/manuscript/25718.html |
| Doi | http://dx.doi.org/10.3413/Nukmed-0743-15-05 |
| Field | Other medical specializations |
| Keywords | Neuroblastoma; I-123-MIBG scintigraphy; I-123-MIBG semiquantitative scoring; Curie scoring; SIOPEN scoring |
| Description | The existing most common semi quantitative systems used for neuroblastoma diagnosis include Curie and SIOPEN scores, which are based on I-123-MIBG planar scans. The purpose of our study was to find out whether a statistically significant difference exists in evaluation based on planar and SPECT/CT scans. Conclusion: We recommend to perform semiquantitative evaluation of neuroblastoma based on SPECT/CT scans, particularly in patients in clinical stages 3 and 4. It is advisable to include soft tissues in the score assessment, as well, given that only soft tissues may be involved in up to 25%. |