Nové léky u akutního srdečního selhání aneb Další zklamání

Title in English New drugs in acute heart/allure or another disappointment
Authors

ŠPINAROVÁ Lenka ŠPINAR Jindřich VÍTOVEC Jiří

Year of publication 2018
Type Article in Periodical
Magazine / Source Remedia
MU Faculty or unit

Faculty of Medicine

Citation
Keywords acute heart failure; natriuretic peptides; vasopressin; serelaxin; positive inotropic substances
Description The search and development ofnew drug classes in heart failure, and acute decompensation in particular, is still ongoing. We present results of clinical studies where natriuretic peptides, adenosine receptor blockers, vasopressin receptor blockers, serelaxin and omecamtiv mecabril, a new positive inotropic substance, are administered to patients. Although these new drug classes translate into advance in clinical care, not even one improves prognosis of patients with heart failure.

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