Ileocaecal Crohn's disease and familial adenomatous polyposis in one patient - a case report
| Authors | |
|---|---|
| Year of publication | 2019 |
| Type | Article in Periodical |
| Magazine / Source | Gastroenterologie a hepatologie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.prolekare.cz/en/journals/gastroenterology-and-hepatology/2019-1-5/ileocaecal-crohn-s-disease-and-familial-adenomatous-polyposis-in-one-patient-a-case-report-108089 |
| Keywords | Bowel continuity restoration; Crohn’s disease |
| Description | Crohn's disease (CD) and familial adenomatous polyposis (FAP) are two diffrent diseases and both affect the gastrointestinal tract.FAP is an autosomal dominant inherited disease; however, the aethiology of CD is still unknown and is supposed to be multifactorial (genetics, environment, immune state, microbiom). The therapy of these two diseases differs as well. The ultimate solution for FAP is surgery (colectomy orproctocolectomy). On the other hand, CD can be treated either conservatively or surgically. Generally, in cases of bowel resection, the alternative of gastointestinal tract restoration has to be considered. This decision is more challenging in patients diagnosed with both diseases (CD and FAP). We present the case of a young female with FAP who was diagnosed with active CD in the ileocaecal region. Due to multiple large colon polyps and a stenotic terminal ileum, she was indicated for surgery (colectomy with terminal ileostomy and terminal ileum resection). Subsequently, an ileorectal anastomosis was construced. In further text, we also discuss other bowel restoration solutions, such as ileal pouch-anal anastomosis and abdominoperineal resection with terminal ileostomy. |