Interakce léčiv se zaměřením na vybrané lékové skupiny v kardiologii

Title in English Drug interactions with a focus on selected drug groups in cardiology


Year of publication 2020
Type Article in Periodical
Magazine / Source Kardiologická revue
MU Faculty or unit

Faculty of Medicine

Keywords interaction; cardiology; pharmacokinetics; pharmacodynamics
Description The risk of drug interactions increases quite logically with the number of drugs used. The numbers vary between studies, however, according to one study, the risk of drug interaction with concomitant use of up to 5 drugs is only 4%, rising to 10% with 5-10 different drugs, over 28% in the group using 11-15 drugs to 54% when taking 16-20 different drugs. There are many reasons and possible explanations and each system has its own specifics - for example, in the absence or malfunction of electronic healthcare and drug records is also a higher probability of duplication. Naturally, the interaction can occur mainly due to inattention or sometimes (in the worst case) due to the ignorance of the doctor or pharmacist. The aim of this article is to review the basic types of interactions and give examples of drug interactions in cardiology.
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