Neočekávaný průběh anti Xa aktivity po suicidálním požití rivaroxabanu u staršího nemocného

Title in English Unexpected course of anti Xa activity after suicidal ingestion of rivaroxaban in an elderly patient
Authors

MATĚJOVSKÁ KUBEŠOVÁ Hana VÝŠKA Ondřej PENKA Miroslav LUDKA Ondřej

Year of publication 2022
Type Article in Periodical
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.prolekare.cz/casopisy/geriatrie-gerontologie
Keywords rivaroxaban; anti Xa; suicidal attempt; pharmacodynamics
Description The authors present a description of the course of a suicidal attempt in an elderly patient with mixed medication, including up to 12 tablets of rivaroxaban with a strength of 20 mg. Monitoring of anti-Xa activity showed its delayed onset compared to the manufacturer‘s data and clinical experience to date. The discussion considers the potential to influence the pharmacokinetics and pharmacodynamics of rivaroxaban with other medications and ethanol used concomitantly.
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