The future for the application of fibroblast growth factor 2 in modern wound healing

Authors

HOLOUBEK Jakub LIPOVÝ Břetislav KNOZ Martin KEMPNÝ Tomáš CHALOUPKOVÁ Radka DAMBORSKÝ Jiří VOJTOVÁ Lucy

Year of publication 2023
Type Article in Periodical
Magazine / Source BURNS
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.sciencedirect.com/science/article/pii/S030541792200273X?via%3Dihub
Doi http://dx.doi.org/10.1016/j.burns.2022.10.007
Keywords fibroblast growth factor 2; wound healing
Description Representatives of the fibroblast growth factor (FGF) family regulate a wide range of biological functions important for every phase of wound healing, such as cell proliferation, migration, and differentiation. The name of the family is derived from the primary assumption that FGF proteins (FGF1 and FGF2) are important for promoting fibroblast migration and proliferation. Today, FGFs are known to intervene in a wide range of biological functions of various cell populations. Their function is mediated by binding to specific receptors (tyrosine-kinase receptors), which leads to their activation and transmembrane signal transduction into the cell.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info