The future for the application of fibroblast growth factor 2 in modern wound healing
|Year of publication
|Article in Periodical
|Magazine / Source
|MU Faculty or unit
|fibroblast growth factor 2; wound healing
|Representatives of the fibroblast growth factor (FGF) family regulate a wide range of biological functions important for every phase of wound healing, such as cell proliferation, migration, and differentiation. The name of the family is derived from the primary assumption that FGF proteins (FGF1 and FGF2) are important for promoting fibroblast migration and proliferation. Today, FGFs are known to intervene in a wide range of biological functions of various cell populations. Their function is mediated by binding to specific receptors (tyrosine-kinase receptors), which leads to their activation and transmembrane signal transduction into the cell.