Pyoderma gangrenosum u nespolupracující pacientky
| Title in English | Uncooperative patient with pyoderma gangraenosum |
|---|---|
| Authors | |
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Referátový výběr z dermatovenerologie |
| MU Faculty or unit | |
| Citation | |
| Web | http://referatovyvyber.cz/dermatovenerologie/images/flippingbook/RVD-4-2022/rvd-4-2022.pdf |
| Keywords | Pyoderma gangraenosum; neutrophil dysfunction; treatment |
| Description | Pyoderma gangraenosum is a re_latively rare disease of unknown etiology, first described more than 100 years ago. It is necessary to think about it in sudden, painful and non-healing ulcers, most often on legs. A lot of patients have systemic di_seases (Crohn's disease, ulcerative colitis, arthritis, malignancies). The treatment is empirical. Treatment can be divided into four categories: topical treatment, systemic non-immunosuppressive therapy, syste_mic immunosuppressive therapy and biological therapy. Ulcers heal with cribriform scars. The course is difficult to predict, often recurrent, depending on the type and severity of comorbidities. |