Clinical and Laboratory Parameters of Carp Edema Virus Disease: A Case Report

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Authors

PAPEŽÍKOVÁ Ivana PIAČKOVÁ Veronika DYKOVÁ Iva BALOCH Ali Asghar KOCOUR KROUPOVÁ Hana ZUSKOVÁ Eliška POJEZDAL Ľubomír MINÁŘOVÁ Hana SYROVÁ Eva BANĎOUCHOVÁ Hana HYRŠL Pavel MATĚJÍČKOVÁ Kateřina PIKULA Jiří PALÍKOVÁ Miroslava

Year of publication 2023
Type Article in Periodical
Magazine / Source Viruses
MU Faculty or unit

Faculty of Science

Citation
Web https://www.mdpi.com/1999-4915/15/5/1044
Doi http://dx.doi.org/10.3390/v15051044
Keywords koi sleepy disease; immunology; respiratory burst; histology
Description In the present study, we describe a natural outbreak of carp edema virus disease (CEVD) in koi carp, concentrating on clinical manifestation, gross and microscopic pathology, immunological parameters, viral diagnostics, and phylogenetic analysis. Examination of white blood cell parameters showed increased monocyte and decreased lymphocyte counts in CEV-affected fish compared to healthy control fish. Regarding immune system functioning, the present work shows, for the first time, enhanced phagocytic activity in CEV-affected fish. Respiratory burst of phagocytes was strongly increased in diseased fish, the increase being attributed to an increased phagocyte count rather than enhancement of their metabolic activity. The present work also newly shows histopathological changes in the pancreatic tissue of diseased koi.

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