Chirurgická liečba gynekomastie vyvolanej bikalutamidom, prehľad vybraných liekov spôsobujúcich nežiaduce účinky-gynekomastiu
| Title in English | Surgical treatment of bicalutamide-induced gynecomastia, an overview of selected drugs causing unwanted effects of gynecomastia |
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| Authors | |
| Year of publication | 2023 |
| Type | Article in Periodical |
| Magazine / Source | Klinická farmakologie a farmacie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.klinickafarmakologie.cz/artkey/far-202304-0005_chirurgicka_liecba_gynekomastie_vyvolanej_bikalutamidom_prehlad_vybranych_liekov_sp_sobujucich_neziaduce_ucink.php |
| Doi | http://dx.doi.org/10.36290/far.2023.028 |
| Keywords | gynecomastia; bicalutamide; prostate cancer; side effects |
| Description | Gynecomastia, the enlargement of male breast tissue, is usually caused by hormonal imbalances between estrogen and testosterone levels. However, it can also be caused by a multitude of factors, such as tumors, obesity, hypogonadism, androgen insensitivity syndrome, thyrotoxicosis, or the use of numerous medications. As an example, we present a patient with gynecomastia which developed after a long-term treatment with bicalutamide for prostate cancer. Due to this adverse effect of his medication, our patient experienced significant anxiety and discomfort in his daily life. Therefore, a bilateral mastectomy in combination with liposuction was chosen for his treatment. Since drug-induced gynecomastia contributes to almost a quarter of all gynecomastia cases, we provide an overview of various other medications responsible for this condition. |