Vztah mezi anamnesticky zjištěnou tělesnou aktivitou a baroreflexní senzitivitou po léčbě antracykliny.

Title in English Relationship between Anamnestically Assessed Physical Activity and Baroreflex Sensitivity after Anthracycline
Authors

HRSTKOVÁ Hana HONZÍKOVÁ Nataša FIŠER Bohumil ZÁVODNÁ Eva NOVOTNÝ Jan

Year of publication 2000
Type Article in Periodical
Magazine / Source Česko-slovenská pediatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords leukaemia; anthracycline therapy; baroreflex; physical activity
Description In the submitted study the authors evaluated the effect of regular physical activity on the development of autonomous regulation of the circulation in children who had previously treatment on account of a malignant tumour, in particular leukaemia, and were treated with cardiotoxic anthracyclines. In 22 children with a history of leukaemia the authors recorded by non- invasive methods the pulse rateat rest, pulse intervals, systolic and diastolic blood prassure and calculated the baroreflex sensitivity of the heard. The childrens physical activity was assessed for one month by means of questionnaires and the approximate value of expended energy was expressed in kJ/kg/day. The authors calculated mean values, standard deviations and mutual correlation coefficients of these variables: age, TI, BPs, BPd, BRS,BRSf, body weight, height, energy expenditure in kJ/kg/day and the body mass index, BMI. By regression analysis they assessed the statistical signifikance of difference in the development of difenrent circulatory parameters and indeces of somatic development with regard to age and therapeutic procedure in children treated with anthracyclines and those not treated with anthracyclines.
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