A modified perfusion system for pharmacological studies in isolated hearts
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Proceedings |
| Conference | Analysis of Biomedical Signals and Images, Biosignal 2000 |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | perfusion set-up;isolated heart;pharmacological studies |
| Description | A modification of the aortic perfusion technique for studying completely isolated mammalian heart convenient for pharmacological studies is presented. The technique enables the experimenter to obtain valuable data from spontaneously beating heart of different species of laboratory animals. Several parameters are recorded (LV pressure, electrogram) using a special software. This system makes it possible to use one heart for several experiments and thus to minimize the number of sacrificed animals. |