Epitheloid hemangioendothelioma of the mandible

Authors

MACHÁLKA Milan

Year of publication 2003
Type Article in Periodical
Magazine / Source Mund-, Kiefer- und Gesichtschirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords bone tumor; epitheloid hemangioendothelioma; mandible
Description The authors describe a locally recurrent tumor of the mandible whose microscopic structure and immunohistochemical findings corresponded to an epitheloid hemangioendothelioma. The tumorous cells had an epitheloid character, they created rudimentary vascular lumina, and they focally expressed vascular markers CD 34, CD 31, and F VIII. Locally the tumor grew aggressively. During the last recurrence, the tumor even affected the already healed and rebuilt bone graft, which was incorporated after the primary resection of the mandibular body. From the histological point of view, the tumor approximated an angiosarcoma. No metastases occurred.
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