Clinical relevance of drug metabolism and metabolic interactions in psychopharmacotherapy

Authors

HADAŠOVÁ Eva

Year of publication 2004
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords Psychotropics; metabolism; cytochromes P450; interactions
Description Major factors of variability in the therapeutic response of psychotropics include genetic polymorphism of metabolizing enzymes (cytochromes P-450, transferases)and drug-drug interactions leading to the enzyme induction or inhibition.
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