Stanovení diklofenaku a 4-hydroxydiklofenaku jako markeru metabolické aktivity CYP2C9
| Title in English | Determination of diclofenac and 4-hydroxydiclofenac as a probe substrate of CYP2C9 |
|---|---|
| Authors | |
| Year of publication | 2005 |
| Type | Article in Proceedings |
| Conference | Sborník abstrakt 34. konference Syntéza a analýza léčiv- Nové směry ve výzkumu léčiv |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | Diclofenac; CYP2C9; determination |
| Description | Diclofenac 4-hydroxylation is commonly used for the CYP2C9 metabolic evaluation. A new rapid, simple and sensitive HPLC method for determination of diclofenac and 4-hydroxydiclofenac was developed. |
| Related projects: |