Srovnání behaviorálních účinků vybraných antidepresiv a kanabidiolu v modelu sociálního stresu u myší
| Title in English | Comparison of behavioural effects of selected antidepressants and cannabidiol in mouse model of social stress |
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| Authors | |
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | citalopram; valproate; cannabidiol; mice; social defeat; animal model |
| Description | The present study compared effects of cannabidiol and antidepressant drugs citalopram and valproate on locomotor behavioural changes in the open field in non-aggressive group-housed male mice which served several times as opponents to aggressive singly-housed mice. The results suggest an antidepressant-like effects of citalopram and valproate and anxiolytic effect of cannabidiol in mice defeated by an aggressive conspecific partner. |
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