Selected endocrine, immune and behavioural changes induced by tiagabine in the olfactory bulbectomy rat model of depression

Authors

PISTOVČÁKOVÁ Jana DOSTÁLEK Miroslav ŠULCOVÁ Alexandra JEŽOVÁ Daniela

Year of publication 2006
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Description The study investigated the influence of tiagabine on stress hormone release, cellular immune function and behaviour in rats following olfactory bulbectomy (OB), a well-recognized animal model of depression. The data acquired support the antidepressant-like action of tiagabine and encourage further research on its use in the treatment of affective disorders.
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