The correlation between pTiO2 and apoptosis in a rat model of a reversible cerebral ischemia - the neuroprotective role or hypertension
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Proceedings |
| Conference | Abstracts - Facing Globalization on Neurological Surgery Update |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | pTiO2; apoptosis; cerebral ischemia; neuroprotective role of hypertension |
| Description | The aim was to proof if there is a correlation between apoptosis and cerebral tissue oxygen (PtO2). This correlation the might be used in a clinical setting for example during temporary clipping in aneurysmal surgery or other types of temporary cerebral vessel occlusion. The results show a close correlation of apoptosis and tissue oxygen in an ischemic brain. Moreover hypertension seems to work as a good neuroprotection since it improved the levels of tissue oxygen and thus decreased the numer of apoptotic cells. |
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