Změny fenotypu CYP2D6 u pacientek s mentální bulimií léčených paroxetinem

• Title in English: Phenotype dynamics of CYP2D6 in mental bulimia patients treated with proxetine
• Authors: PALČÍKOVÁ Ivana; ŽOURKOVÁ Alexandra; VALENTOVÁ Daria; MCCASKEY HADAŠOVÁ Eva
• Year of publication: 2007
• Type: Article in Periodical
• Magazine / Source: Česká a slovenská psychiatrie
• MU Faculty or unit: Faculty of Medicine
• Field: Psychiatry, sexuology
• Keywords: mental bulimia - paroxetine - phenocopy - therapeutic efficacy
• Description: The paper deal with 15 mental bulimia patients and 8 anxiety disroders patients teated with paroxetine, a strong CYP2E6 inhibitor. The faster therapeutic effect was found in patients with inhibition CYP2D6 in both groups.

Related projects

• The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.