Are there gender or seasonal variabilities in mouse behavioral response to acute and chronic ecstasy?

Authors

KUČEROVÁ Jana LANDA Leoš ŠLAIS Karel ŠULCOVÁ Alexandra

Year of publication 2007
Type Article in Periodical
Magazine / Source European Neuropsychopharmacology
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords gender differences; behavioural sensitization; mice; ecstasy; season
Description In this study we summarized and statistically processed results of four experiments of the same design proceeded during aproximately one year to evaluate gender differences on larger groups of mice treated with MDMA, and the females included were intact animals, but also ovariectomized females without or with estrogen substitution in the last experiment. A possibility of seasonal impact on behavioral variabilities was also evaluated.
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