Biofilm formation in non-C. albicans yeasts isolated from blood cultures
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | International Journal of Antimicrobial Agents |
| MU Faculty or unit | |
| Citation | |
| Field | Microbiology, virology |
| Keywords | Biofilm non-C. albicans yeast blood-culture |
| Description | Although C. albicans remains the most common fungal blood stream pathogen, the incidence of non-albicans yeasts has been approached to C. albicans incidence during last few decades. The Eighty-nine strains of non-C. albicans yeasts were isolated from blood cultures and these strains were examined for biofilm formation in this study. The biofilm formation was tested by modification of microtiter plate method. Forty-six strains were positive for biofilm formation. The relatively high percentage of biofilm-positive strains, especially in C. parapsilosis, and C. tropicalis, indicates the important role of biofilm formation as important virulence factor, because these pathogens are frequently associated with indwelling medical devices infections. Increasing incidence of this yeasts in blood stream can be explained by high frequency of using of indwelling medical devices in the few last decades. All tested strains growing in the biofilm showed higher resistance to all antifungal agents in comparison with their planctonic form. |
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