Možnosti aplikace testování aktivity CYP2D6: přehled dosavadních výsledků více než desetileté spolupráce genetiky, farmakologie a psychiatrei

• Title in English: The CYP2D6 activity testing: results of more than 10 years lasting cooperation of genetics, pharmacology and psychiatry
• Authors: ŽOURKOVÁ Alexandra; MCCASKEY HADAŠOVÁ Eva; FLODROVÁ Eva; JUŘICA Jan; KAŠPÁREK Tomáš; ZAHRADNÍKOVÁ Lucia
• Year of publication: 2008
• Type: Article in Periodical
• Magazine / Source: Psychiatrie, časopis pro moderní psychiatrii
• MU Faculty or unit: Faculty of Medicine
• Field: Genetics and molecular biology
• Keywords: personalized medicine; pharmacogenetics; genetic polymorphism; phenotype; genotype; CYP2D6
• Description: The paper summarizes results of studies of clinical correlates of the CYP2D6 dynamics during the treatment of depressive disorder with paroxetine and points out diffrent clinical outcomes according to gener of patients. Indications for assessmnet of the CYP2D6 are further discussed.

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