Imunohistochemická analýza exprese cyklooxygenázy-2 v premaligních a maligních duktálních pankreatických lézích.
| Title in English | Immunohistochemical analysis of cyclooxygenase-2 expression in premalignant and malignant ductal pancreatic lesions. |
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| Authors | |
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská gastroenterologie a hepatologie |
| MU Faculty or unit | |
| Citation | |
| Field | Other specializations of internal medicine |
| Keywords | COX-2; chemoprevention; pancreatic carcinoma; PanIN |
| Description | Immunohistochemical analysis of COX-2 expression showed significant expression of COX-2 in 52,9 % PanIN lesions and in 80 % pancreatic ductal adenocarcinomas. The results supported the concept of pancreatic cancer progression model and of the role of COX-2 in its oncogenesis. |