EFFECT OF BAROREFLEX ON BLOOD PRESSURE VARIABILITY
| Authors | |
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| Year of publication | 2008 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | We studied 58 subjects (20-22 years). Systolic and diastolic blood pressures (SBP, DBP) and inter-beat intervals (IBI) were recorded beat-to-beat for 5 min (Finapres). BRS, and BRSf were determined by the spectral method at 0.1 Hz frequency range. To make a comparison of the quantitative effects of BRS and BRSf on SBPv possible, both variables were expressed as multiples of standard deviations: BRSsd = (BRS – mean BRS) / SD of BRS; BRSfsd = (BRSf – mean BRSf) / SD of BRSf. A negative correlation was found between SBPv and BRSsd (r = - 0.33, p<0.05), and between SBPv and BRSfsd (r = - 0.36, p<0.05). The multiple regression analysis showed higher regression coefficient of BRSfsd than of BRSsd (SBPv = 9.43 – 0.0052*IBI + 0.15*BRSsd – 1.85*BRSfsd, F = 2.92, p<0.05). The analysis revealed that the IBI independent index BRSf [mHz/mmHg] is a better indicator for evaluation of the effectivity of baroreflex sensitivity to suppress the SBP variability than the IBI dependent index BRS [ms/mmHg]. |
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