Erektilní dysfunkce a paraoxonáza: výsledky analýzy z DNA čipu
| Title in English | Erectile dysfunction and paraoxonase: results of DNA chip analysis |
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| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | erectile dysfunction cardiovascular disease paraoxonase 1 PON1 polymorphism gene |
| Description | Erectile dysfunction (ED) is a common problem of middle-aged and elderly men. The etiology of erectile dysfunction is 80% organic and the most frequent cause of ED is cardiovascular disease. Erectile dysfunction and coronary artery disease have the same base and hence the same risk factors. Therefore, coronary artery disease appears in patients with erectile dysfunction and vice versa. Erectile dysfunction can be included in the risk factors of coronary artery disease. Paraoxonase 1 (PON1) has an important role in genesis and in the progress of the atherosclerosis. Atherosclerosis is a common risk factor of erectile dysfunction and coronary artery disease. On 37 males with erectile dysfunction diagnosed by anamnesis, somatosexual examination and by laboratory tests we found the relationship between functional polymorphism of PON1 gene and the age of erectile dysfunction beginning. |
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