Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma
| Authors | |
|---|---|
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Blood |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | multiple myeloma; thalidomide; dexamethasone; melphalane; prednisone |
| Description | We compared thalidomide-dexamethasone with melphalan-prednisolone in 289 elderly patients with multiple myeloma. This is the first trial to compare TD with MP in elderly patients. Results in the TD group showed a significantly higher rate of very good responses (CR and VGPR) and significantly shorter time to response with no difference in time to progression and in progression-free survival. |
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