Genotype Association of C(-735)T Polymorphism in Matrix Metalloproteinase 2 Gene with G(8002)A Endothelin 1 Gene with Plaque Psoriasis

• Authors: VAŠKŮ Vladimír; VAŠKŮ Anna; TSCHÖPLOVÁ Svatava; IZAKOVIČOVÁ HOLLÁ Lydie; SEMRÁDOVÁ Věra; VÁCHA Jiří
• Year of publication: 2002
• Type: Article in Periodical
• Magazine / Source: Dermatology
• MU Faculty or unit: Faculty of Medicine
• Field: Dermatovenerology
• Keywords: MMP-2; Endothelin-1; Gene polymorphism; Plaque psoriasis
• Description: Excessive angiogenesis is one of the characteristic features of psoriasis. To determine the possible genetic background of neo-angiogenesis in plaque psoriasis, frequent polymorphisms in matrix metalloproteinase 2(MMP-2) and endothelin 1(ET-1)genes were studied.

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