Differentiation protocol for hyaline cartilage producing mesenchymal stem cells (MSCs)

Authors

PLÁNKA Ladislav STARÝ David HLUČILOVÁ Jana KLÍMA Jiří KŘEN Loeš NEČAS Alois GÁL Petr

Year of publication 2009
Type Article in Periodical
Magazine / Source EUROPEAN MUSCULOSKELETAL REVIEW
MU Faculty or unit

Faculty of Medicine

Citation
Field Traumatology and orthopaedic surgery
Keywords Mesenchymal stem cells; chondrogenesis;cstilage; differentiation; growth factors
Description An autologous cell transplant can be prepared from the bone marrow and used in the treatment of surface defects of hyaline cartilage and growth-plate defects due to injury or osteosynthesis. As the differentiation cascade of factors is not complete, much research will be necessary to identify the individual factors responsible for successful differentiation and to discover their mutual interaction and sequencing.
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