Způsob stanovení prognózy B-buněčné chronické lymfocytární leukémie

Title in English Method for prognosis determination in B-cell chronic lymphocytic leukemia
Authors

POSPÍŠILOVÁ Šárka KOTAŠKOVÁ Jana TICHÝ Boris MAYER Jiří

Year of publication 2010
Type Patent
MU Faculty or unit

Faculty of Medicine

Publisher Úřad průmyslového vlastnictví
State Czech Republic
Patent's number 301540
Description Method for prognosis determination of chronic lymphocytic leukemia in biological samples based on assesment of LAG3, ZAP70 and LPL gene expression. High expression of these genes correlates with unmutated immunoglobulin heavy chain variable segment gene, more agressive disease and shorter survival.

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