Bakteriologická diverzita akutní a chronické rány
| Title in English | Bacteriological diversity of acute and chronic wounds |
|---|---|
| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Hojení ran |
| MU Faculty or unit | |
| Citation | |
| Field | Microbiology, virology |
| Keywords | wounds bacteria Gram-positive Gram-negative |
| Description | A wound is defined as the impairment of the continuity of skin cover. The skin cannot adequately play its role, particularly as a protective barrier against an infection. The wounds may be classified according several criteria: a course of healing, localization, the extent of tissue defect, age and etiology. From the time point of view they may be divided into acute and chronic wounds. This paper is aimed to define the basic bacterial strains isolated from skin defects and their individual proportional presentation in acute and chronic wounds. Our study was performed in 2006 2008 in the Clinic of Burns and Reconstructive surgery of Faculty Hospital Brno, which is specialized in both acute wounds burns and in chronic wounds particularly decubiti and crural ulcers. There was a total of 213 patients (95 patients with acute wounds, the burns and 118 patients with chronic wounds, decubiti) enrolled in the study. There were 1527 bacterial strains (795 Grampositive and 693 Gramnegative) isolated from the wounds. The most common bacteria cultivated from acute wounds were Staphylococcus coagulase negative (33.4 %), Bacillus sp. (14.8 %), Pseudomonas aeruginosa (10.9 %). The most common bacteria cultivated from chronic wounds were Pseudomonas aeruginosa (16 %), Proteus mirabilis (15.1 %), Staphylococcus aureus (14.2 %). As for the used methods, anaerobic bacteria were assessed only in chronic wounds. There was a total of 39 strains of anaerobic bacteria isolated. Methicilin oxacilin resistant Staphylococcus aureus was isolated only in chronic wounds. From a total of 98 isolated tribes of Staphylococcus aureus the resistance to oxacilin was detected in 31 strains in chronic wounds. Our study confirmed the difference in both qualitative and quantitative proportion of each individual bacteria in acute and chronic wounds. Complex microbiologic monitoring and targeted antibiotic treatment are the keystones of modern treatment of both acute and chronic wounds. |