Potenciální vliv modafinilu u látkových závislostí : ověření behaviorálních účinků u myší
| Title in English | Potential influence of modafinil on drug addiction : examination of its behavioural effects in mice |
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| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Alkoholizmus a drogové závislosti (Protialkoholický obzor) |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | modafinil; behaviour; stimulants; behavioural sensitisation; addiction; mice |
| Description | Modafinil is a drug with psychostimulant effect used in therapy of sleep cycle disorders. Its potential to induce development of behavioural sensitisation and to influence social behaviour was evaluated in present experiments. Using the open field test, development of behavioural sensitisation was shown in animals which received modafinil repeatedly. Modafinil is in this aspect similar to some abused psychostimulants. Modafinil had antiaggressive and anxiolytic effects in the model of conflict social interactions of male mice. |
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